Akademik Bilgiler



HÜSEYİN ONAY
PROFESÖR
Tıp Fakültesi
Dahili Tıp Bilimleri Bölümü
Tıbbi Genetik Anabilim Dalı
Contact Information- E-posta: huseyin.onay@ege.edu.tr
- Telefon: 0 232 3903962, İş
Academic Degree Information- Lisans: Ege Üniversitesi, Tıp Fakültesi, Türkiye, 2002
- Doktora: Ege Üniversitesi, Tıp Fakültesi, Türkiye, 2006
- Yardımcı Doçentlik: Ege Üniversitesi, Tıp Fakültesi, Türkiye, 2007

Research Interests- Genetik (1010103)
- Moleküler Genetik (4010202)
Indexed Journal Publications (22 entries)- Schallreuter KU, Bahadoran P, Picardo M, Slominski A, Elassiuty YE, Kemp EH, Giachino C, Liu JB, Luiten RM, Lambe T, Le Poole IC, Dammak I, Onay H, Zmijewski MA, Dell'Anna ML, Zeegers MP, Cornall RJ, Paus R, Ortonne JP, Westerhof W. Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else? Exp Dermatol. 2008: 17: 139-40: discussion 141-160.
- Onay H, Ugurlu T, Aykut A, Pehlivan S, Inal M, Tinar S, Ozkinay C, Ozkinay F. Rapid Prenatal Diagnosis of Common Aneuploidies in Amniotic Fluid Using Quantitative Fluorescent Polymerase Chain Reaction. Gynecol Obstet Invest. 2008 : 66: 104-110.
- Onay H, Balkan C, Cogulu O, Aydinok Y, Karapinar DY, Ozkinay F. A further Turkish case of Griscelli syndrome with new RAB27A mutation. J Am Acad Dermatol. 2008: 58: 115-116.
- Cosar H, Ozkinay F, Onay H, Bayram N, Bakiler AR, Anıl M, Can D, Ozkınay C. Low levels of mannose-binding lectin confers protection against tuberculosis in Turkish children. Eur J Clin Microbiol Infect Dis. 2008 Jul 9. [Epub ahead of print]
- Cogulu O, Onay H, Uzunkaya D, Gunduz C, Pehlivan S, Vardar F, Atlihan F, Ozkinay C, Ozkinay F. Role of angiotensin-converting enzyme gene polymorphisms in children with sepsis and septic shock. Pediatrics İnternatonal 2008: 50: 477,480.
- Ozkinay F, Pehlivan S, Onay H, Berg P, Vardar F, Koturoglu G, Aksu G, Unal D, Tekgul H, Can S, Ozkinay C. Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infection. J Child Neurol. 2007: 22: 741-743.
- Onay H, Pehlivan M, Alper S, Ozkinay F, Pehlivan S. Might there be a link between mannose binding lectin and vitiligo. Eur J Dermatol. 2007: 17: 146-148.
- Cogulu O, Gunduz C, Karaca E, Onay H, Superti-Furga A, Ozkinay F. Duane anomaly, meningomyelocele, dextroposition of heart and localized vertebrocostal alterations with associated anomalies in a girl. Genet Couns. 2007: 18: 77-83
- Vardar F, Pehlivan S, Onay H, Atlihan F, Guliz N, Ozkinay C, Ozkinay F. Association between mannose binding lectin polymorphisms and predisposition to bacterial meningitis. Turk J Pediatr. 2007: 49: 270-273.
- Koturoglu G, Onay H, Midilli R, Pehlivan S, Eren E, Itirli G, Kurugol Z, Apaydin F, Ozkinay C, Ozkinay F. Evidence of an association between mannose binding lectin codon 54 polymorphism and adenoidectomy and/or tonsillectomy in children. Int J Pediatr Otorhinolaryngol. 2007: 71: 1157-1161.
- Ozkinay F, Kanit H, Onay H, Cogulu O, Gunduz C, Ercal D, Ozkinay C. Prenatal diagnosis of de novo unbalanced translocation 8p:21q using subtelomeric probes. Genet Couns. 2006: 17: 315-320.
- Cogulu O, Gunduz C, Karaca E, Onay H, Ozkinay C, Ozkinay F. Chromosomal rearrangements in children with idiopathic mental retardation using subtelomeric fluorescent in situ hybridization. Genet Couns. 2006: 17: 321-331.
- Ozkinay F, Onay H, Giray O, Cogulu O, Ercal D, Sagol S. A rare chromosomal rearrangement [inv (2)(p11.q13)] was found in a 37-year-old normal male who had an offspring having 46,X,+mar/45,X0. Genet Couns. 2005: 16: 317-318.
- Pehlivan M, Pehlivan S, Onay H, Itirli G, Koyuncuoglu M, Kirkali Z. Can Mycoplasma-Mediated Oncogenesis be Responsible for the Formation of Conventional Renal Cell Carcinoma. World Journal of Urology, 2005: 65: 411-414.
- Ozkinay F, Ercal D, Ozkinay C, Onay H, Bora E, Erler A. Two extra euchromatic bands in the qh region of chromosome 9. Genet Couns. 2005: 16: 45-48.
- Itirli G, Pehlivan M, Alper S, Yuksel SE, Onay H, Ozkinay F, Pehlivan S. Exon-3 polymorphism of CTLA-4 gene in Turkish patients with vitiligo. J Dermatol Sci. 2005: 38: 225-227.
- Cogulu O, Onay H, Ozgenc F, Karaca E, Gunduz C, Tzetis M, Cankaya T, Kanavakis E, Ozkinay F. Trigonocephaly and Wilson's disease in two siblings. Clin Dysmorphol. 2005: 14: 161-164.
- Garg A, Cogulu O, Ozkinay F, Onay H, Agarwal AK. A novel homozygous Ala529Val LMNA mutation in Turkish patients with mandibuloacral dysplasia. J Clin Endocrinol Metab. 2005: 90: 5259-5264.
- 2004, Pehlivan M, Itırli G, Onay H, Bulut H, Koyuncuoglu M, Pehlivan S. Does Mycoplasma sp. Play a Role in Small Cell Lung Cancer.
- Cogulu O, Munanoglu D, Karaca E, Onay H, Ozkinay F. Cleidocranial dysplasia with new additional findings. Genet Couns, 2004: 15: 229-231.
- Gunduz C, Cogulu O, Cankaya T, Bora E, Karaca E, Alpman A, Sagol S, Onay H, Ozkinay F, Ozkinay C. Trends in cytogenetic prenatal diagnosis in a reference hospital in Izmir/Turkey: a comparative study for four years. Genet Couns. 2004:15(1):53-59.
- Alpman A, Bora E, Karaca E, Cankaya T, Onay H, Cogulu O, Gunduz C, Kleijer WJ, Ozkinay F. Detection of trisomy 21 in a fetus during the investigation for Tay-Sachs disease. Genet Couns. 2004:15(1):99-100.

Publications in Non-Indexed Journals (7 entries)- B4. Coşar H, Onay H, Bayram N, Özkınay F. Tüberkülozlu 44 Çocuk hastanın Epidemiyolojik, Klinik ve Prognoz Yönünden Değerlendirilmesi. Çocuk Enfeksiyon Dergisi, 2008: 2: 1-6.
- B5. Pehlivan S, Onay H, Tavmergen E, Tavmergen Göker N, Çoğulu Ö, Özkınay F. Erkek İnfertilitesinde Anjiotensin Konverting Enzim Polimorfizmleri. Gaziantep Tıp Dergisi 2008: 14: 15-17.
- B6. Onay H, Özkınay F, Çoğulu Ö, Kütükçüler N, Sağol S, Özkınay C. Otozomal Resesif SCID ve Prenatal Tanı: Olgu Sunumu. Gaziantep Tıp Dergisi 2008: 14: 47-49.
- B7. Koturoglu G, Vardar F, Özkınay C, Aslan MT, Onay H, Kavaklı K, Kurugol Z, Özkınay F. Geçici Protein C ve Protein S Eksikliğine Bağlı Purpura Fulminans. Çocuk Enf derg 2008: 3: 124-126.
- B1. Pehlivan S, Onay H, Itirli G, Ekmekci A, Unuvar D, Bulut H, Ozkinay F. DNA Replikasyonu ve Tamirinde Görevli DNA Polimerazlar. Arşiv Tıp Dergisi, 2004: 13: 256-278
- B2. Pehlivan M, Onay H, Pehlivan S. DNA Mikroarraylerinin Tıpta Kullanımı Ve Önemi. Arşiv Tıp Dergisi, 2004: 13: 439-447.
- B3. Pehlivan S, Bulut H, Onay H, Itırlı G, Ekmekçi A, Ünüvar D, Özkınay F. RNA Polimerazların Görevleri ve Önemi. Arşiv Tıp Dergisi, 2004: 13: 575-592

International Conference Proceedings (34 entries)- Prenatal Detection of Common Aneuploidies by Quantitative Fluorescence PCR in Turkish Population: Three Years Exprerience in Two Reference Hospitals. XXI European Congress of Perinatal Medicine, Programme Book, 66, 2008, İstanbul, Turkey.
- A retrospective analysis of patients tested for cystic fibrosis mutations in a reference genetics center in Izmir, Turkey. European Human Genetics Conference, European Journal of Human Genetics, Volume 16-Supplement 2, 46, 2008, Barcelona, İspanya
- Primary male infertility in Izmir/Turkey: a cytogenetic and molecular study of 187 infertile Turkish patients. European Human Genetics Conference, European Journal of Human Genetics, Volume 16-Supplement 2, 172, 2008, Barcelona, İspanya
- Is mannose binding lectin codon 54 polymorphism associated with predisposition to acute poststreptococcal glomerulonephritis in childhood? European Human Genetics Conference, European Journal of Human Genetics, Volume 16-Supplement 2, 326, 2008, Barcelona
- Vitamin D Receptor (VDR) Gene Polymorphisms and Susceptibility to Tuberculosis in Izmir/Turkey: A case-control study. Tuberculosis: From Lab Research to Field Trials, Abstract Book, 158, 2007, Vancouver, Kanada.
- Vitamin D Polymorphisms and Susceptibility to Tuberculosis in Turkish Children and Adults. 25th Annual Meeting of the European Society for Pediatric Infectious Diseases-ESPID, Abstract Book, 96, 2007, Porto, Portekiz
- The association between chroid plexus cysts and cytogenetic abnormalities. European Human Genetics Conference, European Journal of Human Genetics, Volume 15-Supplement 1, 132, 2007, Nice, Fransa
- 2007, A retrospective analysis of patients tested for gene polymorphisms implicated in influencing susceptibility to thrombosis in a reference center in Izmir/Turkey. European Human Genetics Conference, European Journal of Human Genetics, Volume 15-Supplement 1
- GENIUS: A new universal stripassay analyzer software. European Human Genetics Conference, European Journal of Human Genetics, Volume 15-Supplement 1, 321, 2007, Nice, Fransa
- Mannose binding lectin codon 54 polymorphism associated with predisposition to Henoch-Schonlein purpura in childhood. The American Society of Human Genetics 57th Annual Meeting, Abstract Book, 157, 2007, San Diego, ABD
- NRAMP1 polymorphisms and susceptibility to tuberculosis in Turkish adult population. The American Society of Human Genetics 57th Annual Meeting, Abstract Book, 450, 2007, San Diego, ABD
- Interferon-: gene and interferon-: receptor 1 gene polymorphisms in tuberculosis children from Turkey. The American Society of Human Genetics 57th Annual Meeting, Abstract Book, 450, 2007, San Diego, ABD
- NRAMP1 polymorphisms and susceptibility to tuberculosis in Turkish children. The American Society of Human Genetics 57th Annual Meeting, Abstract Book, 451, 2007, San Diego, ABD
- NRAMP1 polymorphisms and susceptibility to tuberculosis in Turkish children. The American Society of Human Genetics 57th Annual Meeting, Abstract Book, 451, 2007, San Diego, ABD
- Mannose binding lectin (MBL) gene polymorphisms in children with leukemia and their effects on febrile neutropenic episodes. 24th Annual Meeting of the European Society for Pediatric Infectious Diseases-ESPID, Abstract Book, 17, 2006, Basel, İsviçre
- The role of polymorphisms in the coagulation cascade proteins throughout sepsis in children. 24th Annual Meeting of the European Society for Pediatric Infectious Diseases-ESPID, Abstract Book, 168, 2006, Basel, İsviçre
- The role of angiotensin converting enzyme gene polymorphisms in children with sepsis and septic shock. 24th Annual Meeting of the European Society for Pediatric Infectious Diseases-ESPID, Abstract Book, 168, 2006, Basel, İsviçre
- . MEFV mutations in patients with Familial Mediterranean Fever from the Aegean Region of Turkey. European Human Genetics Conference, European Journal of Human Genetics, Volume 14-Supplement 1, 250, 2006, Amsterdam, Hollanda
- The role of MBL, IL-4, ACE, CCR5 and IL-1RN gene polymorphisms in febrile neutropenia in patients with hematological malignancies. XXXth World Congress of International Congress of Hematology, Abstract Book, 85, 2005, Istanbul
- A further case of Costello syndrome. European Human Genetics Conference, European Journal of Human Genetics, Volume 13-Supplement 1, 93, 2005, Prag, Çek Cumhuriyeti
- A family of ulnar-mammary syndrome with three affected members. European Human Genetics Conference, European Journal of Human Genetics, Volume 13-Supplement 1, 93, 2005, Prag, Çek Cumhuriyeti
- A family of type I BPES with 5 affected members. European Human Genetics Conference, European Journal of Human Genetics, Volume 13-Supplement 1, 94, 2005, Prag, Çek Cumhuriyeti
- Spondylocostal dysplasia in a three generation family with 4 affected members. European Human Genetics Conference, European Journal of Human Genetics, Volume 13-Supplement 1, 94, 2005, Prag, Çek Cumhuriyeti
- Cryptic Chromosomal Abnormalities in Children with Mental Retardation Using Subtelomeric FISH. European Human Genetics Conference, European Journal of Human Genetics, Volume 13-Supplement 1, 146, 2005, Prag, Çek Cumhuriyeti
- Mannose binding lectin gene polymorphism in the patients with sepsis and its effects on prognosis. 23rd Annual Meeting of the European Society for Pediatric Infectious Diseases, Book of Abstracts, 258, 2005, Valencia, İspanya
- The importance of mannose binding lectin gene polymorphisms in acute leukemias and their role in febrile neutropenic episodes. 10th Congress of the European Hematology Association, Abstract Book, 239, 2005, Stockholm, İsveç
- Brucellosis occured during the course of febrile neutopenia due to agranulocytosis: case report. 10th Congress of the European Hematology Association, Abstract Book, 433, 2005, Stockholm, İsveç
- A preliminary study of telomerase activity evuluation in childhood and adult-onset hematological malignancies. XXXth World Congress of International Congress of Hematology, Abstract Book, 182, 2005, İstanbul, Türkiye
- Vitiligo susceptibility and T/C single nucleotide polymorphism in exon 9 of the catalase gene. European Human Genetics Conference, European Journal of Human Genetics, Volume 12-Supplement 1, 295, 2004, Münih, Almanya
- A case of fetal hydantoin syndrome having hemangioma associated with hemiatrophy at the left side of the body. European Human Genetics Conference, European Journal of Human Genetics, Volume 12-Supplement 1, 116, 2004, Münih, Almanya
- Autosomal recessive type SCID and prenatal diagnosis: Case Report. European Human Genetics Conference, European Journal of Human Genetics, Volume 12-Supplement 1, 162, 2004, Münih, Almanya
- A Rare Chromosomal Rearrangement[inv (2)(p11.q13)] Was Found in a 37-Year-Old Normal Male Who Had an Offspring Having 46,X,+mar/45,X0. 4th European Cytogenetics Conference, Annales de Génétique, 254, 2003, Bologna, İtalya
- Unusually elongated secondary constriction with tho bands on chromosome 9 in a normal woman and her normal baby. 4th European Cytogenetics Conference, Annales de Génétique, 263, 2003, Bologna, İtalya
- Seven cases of chromosomal mosaicism detected in amniocenthesis and karyotype, phenotype correlations. European Human Genetics Conference, Final Programme and Abstracts, 283, 2002, Fransa

Referrer Publications (9 entries)- 2008, Title: Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else? Author(s): Schallreuter KU, Bahadoran P, Picardo M, et al. Source: EXPERIMENTAL DERMATOLOGY Volume: 17 Issue: 2 Pages: 139-140 Published: FEB 2008 Times Cited: 3
- 2007, Title: Might there be a link between mannose binding lectin and vitiligo? Author(s): Onay H, Pehlivan M, Alper S, et al. Source: EUROPEAN JOURNAL OF DERMATOLOGY Volume: 17 Issue: 2 Pages: 146-148 Published: MAR-APR 2007 Times Cited: 1
- 2005, Title: A novel homozygous Ala529Val LMNA mutation in Turkish patients with mandibuloacral dysplasia Author(s): Garg A, Cogulu O, Ozkinay F, et al. Source: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM Volume: 90 Issue: 9 Pages: 5259-5264 Published: SEP 2005 Times Cited: 17
- 2005, Title: Exon-3 polymorphism of CTLA-4 gene in Turkish patients with vitiligo Author(s): Itiril G, Pehlivan M, Alper S, et al. Source: JOURNAL OF DERMATOLOGICAL SCIENCE Volume: 38 Issue: 3 Pages: 225-227 Published: JUN 2005 Times Cited: 3
- 2005, Title: Two extra euchromatic bands in the qh region of chromosome 9 Author(s): Ozkinay F, Ercal D, Ozkinay C, et al. Source: GENETIC COUNSELING Volume: 16 Issue: 1 Pages: 45-48 Published: 2005 Times Cited: 1
- 2004, Title: Does Mycoplasma sp play role in small cell lung cancer? Author(s): Pehlivan M, Itirli G, Onay H, et al. Source: LUNG CANCER Volume: 45 Issue: 1 Pages: 129-130 Published: JUL 2004 Times Cited: 4
- 2004, Title: Cleidocranial dysplasia with new additional findings Author(s): Cogulu O, Munanoglu D, Karaca E, et al. Source: GENETIC COUNSELING Volume: 15 Issue: 2 Pages: 229-231 Published: 2004 Times Cited: 2
- 2004, Title: Trends in cytogenetic prenatal diagnosis in a reference hospital in Izmir/Turkey: A comperative study for four years Author(s): Gunduz C, Cogulu O, Cankaya T, et al. Source: GENETIC COUNSELING Volume: 15 Issue: 1 Pages: 53-59 Published: 2004 Times Cited: 1
- 2004, Title: Detection of trisomy 21 in a fetus during the investigation for Tay-Sachs disease Author(s): Alpman A, Bora E, Karaca E, et al. Source: GENETIC COUNSELING Volume: 15 Issue: 1 Pages: 99-100 Published: 2004 Times Cited: 1
Memberships of Professional Associations (3 entries)- American Society of Human Genetics
- Perinatoloji Derneği
- Tıbbi Biyoloji ve Genetik Derneği
Granted Prizes (10 entries)- 2008, 8. Febril Nötropeni Sempozyumu’nda “Akut Lösemilerde İnterlökin 4, Anjiyotensin Dönüştürücü enzim, C
- 2008, Türkiye Psikiyatri Derneği 12. Yıllık Toplantısı/Bahar Sempozyumu’ nda “Psikotik Belirtiler ve Semtl
- 2008, 4. Ulusal Rinoloji Kongresinde “Nazal Polip, MBL Düzeyi ve MBL Polimorfizmlerinden Etkileniyor mu?”
- 2008, 3. Ulusal Osteoporoz Kongresinde “Postmenapozal kadınlarda RANK geni C421T ve C575T polimorfizmlerin
- 2007, 15. Uluslar arası Neonatoloji Kongresi’ nde “Mannoz Bağlayan Lektin Gen Mutasyonu ve Neonatal Sepsis
- 2006, 7. Febril Nötropeni Sempozyumu’nda ‘Lösemili Çocuklarda Mannoz Bağlayıcı Lektin Gen Polimorfizmleri
- 2005, 6. Febril Nötropeni Simpozyumu’nda ‘Akut lösemilerde mannoz bağlayıcı lektin genindeki polimorfizmle
- 2005, 10. Roche Tıp Ödülleri’ nde ‘Significance of heat shock protein-27 expression in patients with renal
- 2005, 4. Ulusal Çocuk Enfeksiyon Hastalıkları Kongresi’ nde ‘Sepsis Hastalarında Mannoz Bağalayan Lektin G
- 2004, 40. Türk Pediatri Kongresi’nde “Bakteriyel menejitlere yatkınlık ve mannoz bağlayan lektin polimorfi