Akademik Bilgiler



ÇİĞDEM SELLİ
DOÇENT
Eczacılık Fakültesi
Eczacılık Meslek Bilimleri Bölümü
Farmakoloji Ana Bilim Dalı
İletişim Bilgileri- E-posta: cigdem.selli@ege.edu.tr
- E-posta: cigdemselli@gmail.com
- Telefon: 232 3885266
Eğitim Bilgileri- Lisans: Ege Üniversitesi, Eczacılık Fakültesi, Türkiye, 2002
- Yüksek Lisans: Ege Üniversitesi, Eczacılık Fakültesi, Farmakoloji AbD, Türkiye, 2005
- Doktora: Ege Üniversitesi, Eczacılık Fakültesi, Farmakoloji AbD, Türkiye , 2011

İdari ve Akademik Görevleri (5 adet)- Doçent (Farmakoloji), 2017-
- Visiting Scientist, University of Edinburgh, 2017-
- Research Fellow, The University of Edinburgh, 2015-2017
- EMBO Fellow, The University of Edinburgh, 2013
- Araştırma Görevlisi, Ege Universitesi, 2002-2017
İndekslerce Taranan Dergilerdeki Yayınları (17 adet)- 2016, Selli C, Dixon JM, Sims AH. Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers. Breast Cancer Res 18:118.
- 2016, Selli C, Pearce DA, Sims AH, Tosun M. Differential expression of store-operated calcium- and proliferation-related genes in hepatocellular carcinoma cells following TRPC1 ion channel silencing. Mol Cell Biochem 420(1-2):129-40.
- 2016, Selli C, Tosun M. Effects of cyclopiazonic acid and dexamethasone on serotonin-induced calcium responses in vascular smooth muscle cells. J Physiol Biochem 72(2):245-53.
- 2016, Erac Y, Selli C, Tosun M. Effects of cell seeding density on real-time monitoring of anti-proliferative effects of transient gene silencing. J of Biol Res-Thessaloniki 23:20.
- 2016, Erac Y, Selli C, Tosun M. TRPC1 ion channel gene regulates store-operated calcium entry and proliferation in human aortic smooth muscle cells. Turk J Biol, 40: doi:10.3906/biy-1602-57.
- 2016, Erac Y, Selli C, Tosun M. Alterations of store-operated calcium entry and cyclopiazonic acid-induced endothelium-derived relaxations in aging rat thoracic aorta. Physiol Int, 103(2): 146-156.
- 2016, Selli C, Erac Y, Tosun M. Effects of 1-(2-trifluoromethylphenyl)-imidazole (TRIM) on receptor-independent 1 and -dependent contractile responses in rat aorta. Turk J Med Sci 46: 1209-1214.
- 2015, Selli C, Erac Y, Tosun M. Simultaneous measurement of cytosolic and mitochondrial calcium levels: Observations in TRPC1-silenced hepatocellular carcinoma cells. J Pharmacol Toxicol Methods 72: 29-34.
- 2015, Selli C, Erac Y, Kosova B, Erdal ES, Tosun M. Silencing of TRPC1 regulates store-operated calcium entry and proliferation in Huh7 hepatocellular carcinoma cells. Biomed & Pharmacother 71:194-200.
- 2014, Selli C*, Erac Y, Tosun M. Cyclopiazonic acid alters serotonin-induced responses in rat thoracic aorta. Vascul Pharmacol. 61(2-3): 43-48.
- 2014, Erac Y, Selli C, Filik P, Tosun M. Effects of passage number on proliferation and store-operated calcium entry in A7r5 vascular smooth muscle cells. J Pharmacol Toxicol Methods 70 (1): 1-5.
- 2014, Selli C, Yıldırım G, Kaymak A, Karacicek B, Ogut D, Gungor T, Erem E, Ege MA, Bümen N, Tosun M. Introducing basic molecular biology to Turkish rural and urban primary school children via hands-on PCR and gel electrophoresis activities. Biochem Mol Biol Educ 42(2): 114-120.
- 2010, Erac Y, Selli C, Kosova B, Akcali KC and Tosun M. “Expression levels of TRPC1 and TRPC6 ion channels are reciprocally altered in aging rat aorta: implications for age-related vasospastic disorders.” Age (32) 223-230.
- 2009, Selli C, Erac Y, Kosova B, Tosun M. Post-transcriptional silencing of TRPC1 ion channel gene by RNA interference upregulates TRPC6 expression and store-operated Ca2+ entry in A7r5 vascular smooth muscle cells. Vascul Pharmacol (51) 96-100.
- 2009, Erac Y, Selli C, and Tosun M. Role of Endothelium on Cyclopiazonic Acid-induced Vascular Contractions in Rat Aorta. Hacettepe University Journal of Faculty of Pharmacy; 28 (2):149-160.
- 2009, Erac Y, Selli C, Tosun M. Role of TRPC ion channels in versatile functions of calcium. (Turkish) Hacettepe University Journal of Faculty of Pharmacy; 28 (2):161-183.
- 2007, Tosun M, Erac Y, Selli C and Karakaya N. Sarcoplasmic-endoplasmic reticulum Ca2+ ATPase inhibition prevents endothelin A receptor antagonism in rat aorta. Am J Physiol Heart Circ Physiol 292:H1961-H1966.

İndekslerce Taranmayan Dergilerdeki Yayınları (2 adet)- 2009, Yasemin Eraç, Çiğdem Selli, Metiner Tosun “Role of Endothelium on Cyclopiazonic Acid-induced Vascular Contractions in Rat Aorta.” Hacettepe University Journal of Faculty of Pharmacy,V28:35-46.
- 2009, Yasemin Eraç, Çiğdem Selli, Metiner Tosun “Kalsiyumun Çok Yönlü İşlevselliğinde TRPC İyon Kanallarının Rolü.” Hacettepe University Journal of Faculty of Pharmacy, V28:47-70.

Tamamlanmış Araştırma Projeleri (10 adet)- 2016, The University of Edinburgh, Identification of a gene signature to predict ER+ breast cancer dormancy by transcriptome analysis of matched pre- and extended-neoadjuvant treatment biopsies
- 2015, EUBAP-14ECZ022, Effects of SERCA blockade on endothelin and serotonin receptor antagonism and internalization
- 2015, EU H2020-MSCA-IF, 658170, Molecular characterisation of a clinical model of estrogen receptor-positive breast cancer dormancy
- 2014, Tübitak Bilim ve Toplum Projesi 113B026, Molecular Biology Laboratory Summer School, Hands on training to develop life sciences awareness in 8th-grade school students
- 2013, Tübitak Bilim ve Toplum Projesi 112B052, Molecular Biology Laboratory Summer School, Hands on training to develop life sciences awareness in 8th-grade school students
- 2010, Tübitak Projesi 110S096, Functional genomics analysis of miRNA expressional profile associated with post-transcriptional control of TRPC ion channel genes in human primary aortic smooth muscle cells
- 2008, EUBAP-06ECZ013, siRNA-mediated silencing of TRPC protein expression in cell culture
- 2005, Tübitak Projesi, TRPC Gen Ailesinin Karsinojenezdeki İşlevsel Ekspresyon Kalıbının Post-Transkripsiyonel Gen Susturma ile Araştırılması
- 2004, Tübitak Projesi, Pharmacological and molecular approaches in controlling capacitative Ca2+ entry in vasospasm development
- 2002, Ege University Research Project EUBAP-02ECZ006, The role of intracellular Ca2+ stores and compartments in development of receptor-mediated vasospasm
Bilimsel Kuruluş Üyeliklerim (8 adet)- British Association for Cancer Research
- Çağdaş Eczacılar Derneği
- European Association for Cancer Research
- Marie Curie Alumni Association
- TEMA
- The Biochemical Society, UK
- Türk Farmakoloji Derneği
- Türkiye Kızılay Derneği
Kazanılan Burslar (3 adet)- 2015, Marie Sklodowska Curie Bursu
- 2013, Avrupa Moleküler Biyoloji Organizasyonu (EMBO) Bursu
- 2005, TÜBİTAK Yurt İçi Doktora Burs Programı-BİDEP 2211
Kazandığı Ödüller (8 adet)- 2012, Poster üçüncülük ödülü, 4 th International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium signaling and TRPchannels
- 2010, En iyi poster ödülü, 3rd International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium signaling and TRPchannels
- 2010, Novartis Farmakoloji Dalı Araştırma Ödülü (Birincilik)
- 2010, TÜBİTAK Uluslararası Bilimsel Yayın Teşvik Ödülü
- 2009, TÜBİTAK Uluslararası Bilimsel Yayın Teşvik Ödülü
- 2008, Novartis Farmakoloji Dalı Araştırma Destek Ödülü
- 2007, TÜBİTAK Uluslararası Bilimsel Yayın Teşvik Ödülü
- 2006, Novartis Farmakoloji Dalı Araştırma Ödülü (Üçüncülük)